Masanori Matsumoto Selected Research

von Willebrand Factor

4/2022	Ratio of von Willebrand factor antigen to ADAMTS13 activity is a useful biomarker for acute-on-chronic liver failure development and prognosis in patients with liver cirrhosis.
3/2022	ADAMTS13, VWF, and Endotoxin Are Interrelated and Associated with the Severity of Liver Cirrhosis via Hypercoagulability.
1/2022	Increased cleavage of von Willebrand factor by ADAMTS13 may contribute strongly to acquired von Willebrand syndrome development in patients with essential thrombocythemia.
10/2021	Analysis focusing on plasma von Willebrand factor in pachychoroid neovasculopathy and age-related macular degeneration.
6/2021	Hemolysis and von Willebrand factor degradation in mechanical shuttle shear flow tester.
12/2020	Association between ADAMTS13 activity-VWF antigen imbalance and the therapeutic effect of HAIC in patients with hepatocellular carcinoma.
11/2020	Novel aptamer to von Willebrand factor A1 domain (TAGX-0004) shows total inhibition of thrombus formation superior to ARC1779 and comparable to caplacizumab.
3/2020	Identification of a missense mutation (p.Leu1733Pro) in the A3 domain of von Willebrand factor in a family with type 2M von Willebrand disease.
1/2020	Plasma Level of von Willebrand Factor Propeptide at Diagnosis: A Marker of Subsequent Renal Dysfunction in Autoimmune Rheumatic Diseases.
1/2020	[Diagnosis and treatment of thrombotic thrombocytopenic purpura].

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Masanori Matsumoto Research Topics

Disease

72	Thrombotic Thrombocytopenic Purpura 08/2022 - 01/2002
21	Thrombocytopenia (Thrombopenia) 04/2021 - 05/2006
20	Thrombotic Microangiopathies 01/2021 - 12/2003
19	Thrombosis (Thrombus) 01/2022 - 02/2003
16	acquired Thrombotic thrombocytopenic purpura 06/2022 - 09/2002
13	Hemolytic-Uremic Syndrome 01/2022 - 01/2002
12	Hemolytic Anemia 02/2022 - 12/2006
11	Hemorrhage 02/2022 - 01/2002
10	Inflammation (Inflammations) 01/2022 - 09/2008
10	Neoplasms (Cancer) 12/2020 - 01/2004
7	Atypical Hemolytic Uremic Syndrome 01/2019 - 11/2014
6	Liver Cirrhosis (Hepatic Cirrhosis) 04/2022 - 08/2009
5	Hemolysis 06/2021 - 02/2007
5	Liver Diseases (Liver Disease) 01/2017 - 08/2005
5	Renal Insufficiency (Renal Failure) 08/2016 - 01/2005
4	Disseminated Intravascular Coagulation 04/2021 - 01/2018
4	Hepatocellular Carcinoma (Hepatoma) 12/2020 - 11/2018
4	Autoimmune Diseases (Autoimmune Disease) 10/2020 - 01/2004
4	Disease Progression 10/2018 - 01/2005
4	Connective Tissue Diseases (Connective Tissue Disease) 01/2013 - 08/2009
3	Thrombophilia 03/2022 - 05/2019
3	COVID-19 02/2022 - 04/2021
3	Infections 01/2022 - 01/2010
3	Reperfusion Injury 11/2019 - 12/2005
3	Fibrosis (Cirrhosis) 10/2019 - 06/2008
3	Fever (Fevers) 01/2013 - 12/2006
2	Evans Syndrome 01/2022 - 10/2005
2	Macular Degeneration (Age-Related Maculopathy) 10/2021 - 01/2018
2	Wounds and Injuries (Trauma) 06/2021 - 09/2008
2	Constipation 01/2021 - 01/2021
2	Ischemia 01/2021 - 12/2005
2	Esophageal and Gastric Varices (Esophageal Varices) 12/2020 - 04/2020
2	Aortic Valve Stenosis (Aortic Stenosis) 01/2020 - 10/2016
2	von Willebrand Diseases (von Willebrand's Disease) 11/2018 - 02/2003
2	Brain Diseases (Brain Disorder) 02/2018 - 04/2015
2	Multiple Organ Failure (MODS) 02/2018 - 09/2017
2	Hepatitis 09/2017 - 01/2010
2	Human Influenza (Influenza) 09/2016 - 01/2010
2	Pancreatitis 04/2016 - 01/2008
2	Acute Kidney Injury (Acute Renal Failure) 04/2015 - 05/2013

Drug/Important Bio-Agent (IBA)

63	thiamine triphosphorate (TTP)IBA 06/2022 - 05/2002
35	von Willebrand FactorIBA 04/2022 - 02/2003
13	Metalloproteases (Metalloproteinases)IBA 06/2022 - 10/2004
13	AutoantibodiesIBA 01/2021 - 01/2002
11	Rituximab (Mabthera)FDA Link 08/2022 - 06/2005
11	ThrombospondinsIBA 06/2022 - 10/2004
11	AntigensIBA 04/2022 - 01/2007
10	DisintegrinsIBA 06/2022 - 10/2004
10	ADAMTS13 ProteinIBA 01/2017 - 01/2002
6	SteroidsIBA 01/2022 - 01/2005
6	Immunoglobulin G (IgG)IBA 11/2019 - 12/2002
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2005
4	Biomarkers (Surrogate Marker)IBA 04/2022 - 11/2018
4	Messenger RNA (mRNA)IBA 02/2022 - 08/2005
4	AntibodiesIBA 11/2021 - 10/2005
4	Dacarbazine (DIC)FDA LinkGeneric 04/2021 - 01/2018
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2002
4	eculizumab FDA Link 01/2019 - 04/2015
4	Complement System Proteins (Complement)IBA 10/2018 - 11/2014
4	CytokinesIBA 02/2018 - 02/2010
3	EnzymesIBA 04/2022 - 01/2002
3	EndotoxinsIBA 03/2022 - 02/2010
3	caplacizumabIBA 01/2022 - 01/2020
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2019 - 01/2018
3	Intravenous Immunoglobulins (IVIG)FDA Link 07/2019 - 02/2007
3	Ticlopidine (Ticlid)FDA LinkGeneric 06/2013 - 02/2009
3	CollagenIBA 09/2012 - 02/2003
2	GlucocorticoidsIBA 08/2022 - 04/2017
2	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2022 - 10/2005
2	Factor VIII (Coagulation Factor VIII)IBA 02/2022 - 01/2008
2	VaccinesIBA 02/2022 - 01/2022
2	Interleukin-17 (Interleukin 17)IBA 01/2022 - 11/2017
2	ARC 1779IBA 01/2022 - 11/2020
2	antineoplaston A10 (A 10)IBA 11/2021 - 11/2017
2	AnticoagulantsIBA 04/2021 - 02/2007
2	Lubiprostone FDA Link 01/2021 - 01/2021
2	Capsules (Microcapsules)IBA 12/2020 - 09/2017
2	botrocetinIBA 11/2020 - 07/2012
2	Glycoproteins (Glycoprotein)IBA 11/2020 - 04/2019
2	Hyaluronic Acid (Hyaluronan)IBA 04/2020 - 05/2010
2	Hemostatics (Antihemorrhagics)IBA 04/2020 - 01/2011
2	BilirubinIBA 11/2018 - 12/2016
2	Monoclonal AntibodiesIBA 11/2017 - 02/2008
2	Interleukin-8 (Interleukin 8)IBA 09/2017 - 02/2010
2	InterleukinsIBA 09/2017 - 02/2010
2	ThrombomodulinIBA 04/2015 - 01/2013
2	Bevacizumab (Avastin)FDA Link 01/2015 - 01/2013
2	Interleukin-10 (Interleukin 10)IBA 12/2014 - 01/2013
2	CreatinineIBA 05/2013 - 12/2005
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2013 - 02/2010
2	Clopidogrel (Plavix)FDA Link 11/2012 - 02/2009

Therapy/Procedure

18	Plasma Exchange 08/2022 - 05/2002
13	Therapeutics 06/2022 - 12/2002
5	Drug Therapy (Chemotherapy) 12/2020 - 10/2008
4	Liver Transplantation 07/2015 - 12/2003
3	Plasmapheresis 01/2022 - 12/2006
3	Platelet Transfusion (Blood Platelet Transfusions) 01/2022 - 03/2016
3	Ligation 12/2020 - 08/2009
3	Hepatectomy 11/2019 - 03/2010
2	Heart-Assist Devices 06/2021 - 01/2020